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TLS Online TPP Program

#Question id: 4319

Why are BRCA1 and BRCA2 considered to be tumor-suppressor genes?

#Part-A Aptitude & General Biotechnology

  1. Their normal products participate in repair of DNA damage.

  2. The mutant forms of either one of these prevent breast cancer.

  3. The normal genes make estrogen receptors.

  4. They block penetration of breast cells by chemical carcinogens.

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TLS Online TPP Program

#Question id: 19791

#Part-A Aptitude & General Biotechnology

Which of the following statements about polymerase chain reaction is correct?
a) PCR denaturation temperature calculated by using Y = X (1+E)n
b) Size of the primer negatively affects the efficiency of PCR
c) Standard PCR doesn’t efficiently amplify sequence much longer than about 5kb.
d) Primer annealing of PCR at 550C for 1.5 min.
e) Time taken for each cycle of PCR considerably longer than 3 min.
TLS Online TPP Program

#Question id: 19791

#Part-A Aptitude & General Biotechnology

Which of the following statements about polymerase chain reaction is correct?
a) PCR denaturation temperature calculated by using Y = X (1+E)n
b) Size of the primer negatively affects the efficiency of PCR
c) Standard PCR doesn’t efficiently amplify sequence much longer than about 5kb.
d) Primer annealing of PCR at 550C for 1.5 min.
e) Time taken for each cycle of PCR considerably longer than 3 min.
TLS Online TPP Program

#Question id: 19840

#Part-A Aptitude & General Biotechnology

Match the following source of thermostable DNA polymerase with proofreading (3’−5’ exonuclease) activity;

                 DNA Polymerase

                        Sources

 

 A- Tma

 

i) Pyrococcus furiosus

 

 B- Deep VentTM

 

ii) Pyrococcus woesi

 

 C- Tli

 

iii)  Thermotoga maritima

 

 D- Pfu

 

iv) Pyrococcus sp.

 

 E- Pwo

 

v) Thermococcus litoralis

TLS Online TPP Program

#Question id: 19840

#Part-A Aptitude & General Biotechnology

Match the following source of thermostable DNA polymerase with proofreading (3’−5’ exonuclease) activity;

                 DNA Polymerase

                        Sources

 

 A- Tma

 

i) Pyrococcus furiosus

 

 B- Deep VentTM

 

ii) Pyrococcus woesi

 

 C- Tli

 

iii)  Thermotoga maritima

 

 D- Pfu

 

iv) Pyrococcus sp.

 

 E- Pwo

 

v) Thermococcus litoralis

TLS Online TPP Program

#Question id: 19841

#Part-A Aptitude & General Biotechnology

Which of the following is true regarding Reverse transcriptase ?
TLS Online TPP Program

#Question id: 19841

#Part-A Aptitude & General Biotechnology

Which of the following is true regarding Reverse transcriptase ?