For an application where you require a sample of your target protein at high purity, what would be a good purification strategy? Assume that your starting point is E. coli cells in which the target protein fused to an affinity tag has been over-expressed.

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#Question id: 14135

#Part-B Specialized Branches in Biotechnology

Which of the following statement is correct about PAM matrix? 

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#Question id: 14135

#Part-A Aptitude & General Biotechnology

Which of the following statement is correct about PAM matrix? 

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#Question id: 14136

#Part-B Specialized Branches in Biotechnology

Which of the following statement is incorrect about global alignment? 

(A) Global alignment is based on the Needleman–Wunsch algorithm.

(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.

(C) It is only suitable for aligning two closely related sequences that are of the same length.

(D) GAP is a web-based pairwise global alignment program.

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#Question id: 14136

#Part-A Aptitude & General Biotechnology

Which of the following statement is incorrect about global alignment? 

(A) Global alignment is based on the Needleman–Wunsch algorithm.

(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.

(C) It is only suitable for aligning two closely related sequences that are of the same length.

(D) GAP is a web-based pairwise global alignment program.

TLS Online TPP Program

#Question id: 14137

#Part-B Specialized Branches in Biotechnology

Consider the following alignment of two DNA sequences:

                            AGTAAC

                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________

TLS Online TPP Program

#Question id: 14137

#Part-A Aptitude & General Biotechnology

Consider the following alignment of two DNA sequences:

                            AGTAAC

                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________