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TLS Online TPP Program

#Question id: 762

Regarding the sugar residues in nucleic acids, which, if any, of the following statements is incorrect?

#Part-B Specialized Branches in Biotechnology

  1. The sugar is always based on a heterocyclic ring that consists of one oxygen atom and four carbon atoms, one of which is connected to a fifth carbon atom, the 5’ carbon atom.

  2. The internal sugar residues in a DNA strand normally have free hydroxyl groups, unlike those in an RNA strand.

  3. Bases are covalently linked to the carbon 1’ atoms of the sugars.

  4. Neighboring sugar residues are linked to each other by a phosphodiester bond that connects the 3’ carbon atom on one sugar to the 5’ carbon atom of its neighbour.

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TLS Online TPP Program

#Question id: 14137

#Part-A Aptitude & General Biotechnology

Consider the following alignment of two DNA sequences:
                            AGTAAC
                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________
TLS Online TPP Program

#Question id: 14138

#Part-B Specialized Branches in Biotechnology

BLAST uses heuristics to align a query sequence with all sequences in a database. 
Reason(R): BLASTX uses protein sequences as queries to search against a protein sequence database.
TLS Online TPP Program

#Question id: 14138

#Part-A Aptitude & General Biotechnology

BLAST uses heuristics to align a query sequence with all sequences in a database. 
Reason(R): BLASTX uses protein sequences as queries to search against a protein sequence database.
TLS Online TPP Program

#Question id: 14139

#Part-B Specialized Branches in Biotechnology

Which of the following statement is incorrect about sequence similarity and sequence identity? 
TLS Online TPP Program

#Question id: 14139

#Part-A Aptitude & General Biotechnology

Which of the following statement is incorrect about sequence similarity and sequence identity? 
TLS Online TPP Program

#Question id: 14140

#Part-B Specialized Branches in Biotechnology

In sequence alignment by BLAST, each word from query sequence is typically _______ residues for protein sequences and _______ residues for DNA sequences.