Practice Questions

  1. Home
  2. Free Resources
  3. Practice Questions
  4. 23715
TLS Online TPP Program

#Question id: 799

The two cleavage reactions required to generate the miRNA from these primary transcripts are mediated by two distinct RNases. A characteristic of both these enzymes is that they recognize and cleave RNAs on the basis of the structure of their substrates rather than their specific sequence. Which of the following statement is INCORRECT regarding the cleavage reactions that produces a mature RNA?

#Part-B Specialized Branches in Biotechnology

  1. Drosha resides in the cell’s nucleus, and the Drosha-catalyzed cleavage event occurs in that cellular compartment that generates a pre-miRNA which is ~65–70 nucleotides long.

  2. The pre-miRNA liberated by Drosha is exported to the cytoplasm, where the second RNA cleavage reaction, performed by Dicer, takes place which cleaves pre-miRNA 22 nucleotides from its ends.

  3. For processing by Drosha, ssRNA lacking significant secondary structure, is needed flanking each side (5’ and 3’) of the stem-loop. It is the ssRNA–dsRNA junctions that are in responsible for determining the cleavage specificity of Drosha.

  4. The RNase II family enzymes are specific for dsRNA and cleave it in a manner that leaves a 2-nucleotide overhang on the 3’ ends of the dsRNA product. This 3’ overhang is important for recognition of that RNA molecule by the next enzyme in the pathway, Dicer.

More Questions
TLS Online TPP Program

#Question id: 3519

#Part-A Aptitude & General Biotechnology

If quadruple heterozygote of genotype Aa Bb Cc Dd is self-fertilized, what is the probability of a quadruple heterozygote Aa Bb Cc Dd offspring is assuming independent assortment of all four pairs of alleles.
TLS Online TPP Program

#Question id: 3520

#Part-A Aptitude & General Biotechnology

flower colour  in plant  RR- red , rr- white , Rr- pink  and height of plant ( TT,Tt-tall)  ,(tt- dwarf), If cross allowed between plant RrTt X Rrtt, then what probability of progeny plant having pink flower and dwarf variety ?
TLS Online TPP Program

#Question id: 3521

#Part-A Aptitude & General Biotechnology

Which of the following is incorrect about independent assortment?
TLS Online TPP Program

#Question id: 3522

#Part-A Aptitude & General Biotechnology

A haplo-diplod insect, Male are haploid but female are diploid, A female who is heterozygous for recessive red eye color mutation mate with red eye male. What will be percent of wild phenotype color eye among their female?
TLS Online TPP Program

#Question id: 3523

#Part-A Aptitude & General Biotechnology

If the number of heterozygous pairs involved in a particular cross is three, the phenotype ratio obtained in their F2 generation will be-
TLS Online TPP Program

#Question id: 3523

#Part-B Specialized Branches in Biotechnology

If the number of heterozygous pairs involved in a particular cross is three, the phenotype ratio obtained in their F2 generation will be-