TLS Online TPP Program

#Question id: 861


Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of

i. Only 2 to 3 minutes,

B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of

ii. >10 hours in prokaryotes

iii. >20 hours in eukaryotes.

#Part-B Specialized Branches in Biotechnology
  1. A-II &III

  2. B-II &III

  3. A-I and B-II & III

  4. B-I and A-II & III