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TLS Online TPP Program

#Question id: 11134

Which of the following statements concerning synaptic transmission is correct?

#Part-B Specialized Branches in Biotechnology
  1. When a specific population of synaptic terminals is spread over the considerable surface of a neuron, their collective effects cannot spatially summate and lead to initiation of an action potential
  2. Even if the successive discharges of an excitatory synapse occur sufficiently close in time, they cannot temporally summate and initiate an action potential
  3. A neuron is “facilitated” when its membrane potential is moved in the less negative or depolarizing direction
  4. Even when rapidly stimulated by excitatory synaptic input for a prolonged period of time, neurons typically do not exhibit synaptic fatigue
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TLS Online TPP Program

#Question id: 852

#Part-B Specialized Branches in Biotechnology

.________ enzyme revealed the relation between the amino acid sequence of a protein and its conformation.
TLS Online TPP Program

#Question id: 854

#Part-B Specialized Branches in Biotechnology

Many conditions including type 2 diabetes, Alzheimer  disease, Huntington disease and parkinson disease are associated with the misfolding mechanism a soluble protein that is normally secreted from the cell is secreted in the missfold state and converted into an insoluble extracellular fibre the diseases are correctly referred to as
TLS Online TPP Program

#Question id: 857

#Part-B Specialized Branches in Biotechnology

The aggregation of nonpolar side chains in the interior of a protein is favored by
TLS Online TPP Program

#Question id: 859

#Part-B Specialized Branches in Biotechnology

Which one statement is incorrect about ATG genes;
TLS Online TPP Program

#Question id: 861

#Part-B Specialized Branches in Biotechnology

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of

i. Only 2 to 3 minutes,

B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of

ii. >10 hours in prokaryotes

iii. >20 hours in eukaryotes.

TLS Online TPP Program

#Question id: 863

#Part-B Specialized Branches in Biotechnology

Ubiquitinated proteins are proteolytically degraded in an ATP-dependent process mediated by a large (∼2500 kD, 26S) multiprotein complex named the 26S proteasome;