TLS Online TPP Program

#Question id: 12494


Hunter syndrome is a rare form of mucopolysacchararidosis that differs from all other forms in that it shows X-linked recessive inheritance. A woman with two affected brothers is referred for genetic counselling. Which of the following is correct?

#Part-A Aptitude & General Biotechnology
  1. The probability that she is a carrier is 2/3.
  2. If she is a carrier then the probability that each of her sons will be affected is 1 in 4.
  3. If she is a carrier then the probability that each of her daughters will be a carrier is 1 in 4.
  4. Before any carrier testing is carried out the woman can be correctly informed that the probability that her first son will be affected is 1 in 4.