The series of events by which APC/C promotes the separation of sister chromatids at anaphase.

A. all the kinetochores have attached to spindle microtubules and the spindle apparatus is properly assembled and oriented.

B. Cdc20 specificity factor associated with APC/C directs it to ubiquitinylate securin and mitotic cyclins. 

C. A protease known as separase cleaves the cohesin subunit Scc1 (Rad21), breaking the protein circles linking sister chromatids.

D. anaphase begins as poleward force exerted on the kinetochores moves the split sister chromatids toward opposite spindle poles.

E. Following securin degradation and a decrease in mitotic CDK activity.

Which of the following series is correct?

#Question id: 887

#Part-B Specialized Branches in Biotechnology

Polypeptides fold rapidly by a stepwise process, how does the polypeptide chain arrive at its native conformation?

#Question id: 887

#Part-A Aptitude & General Biotechnology

Polypeptides fold rapidly by a stepwise process, how does the polypeptide chain arrive at its native conformation?

#Question id: 891

#Part-B Specialized Branches in Biotechnology

The folding pathways of some proteins require two enzymes that catalyze isomerization reactions such as,

a) Peptide prolyl isomerase (PPI)  catalyzes the elimination of folding intermediates with inappropriate disulfide cross-links

b) Protein disulfide isomerase (PDI) enzyme that catalyzes the interchange, or shuffling, of disulfide bonds until the bonds of the native conformation are formed

c) Peptide prolyl cis-trans isomerase (PPI) catalyzes the interconversion of the cis and trans isomers of Proline residue peptide bonds

d) Peptide prolyl isomerase (PPI) can be a fast step in the folding of proteins that contain some Pro peptide bonds in the cis conformation

Which of the following combinations is correct about protein folding pathways?

#Question id: 891

#Part-A Aptitude & General Biotechnology

The folding pathways of some proteins require two enzymes that catalyze isomerization reactions such as,

a) Peptide prolyl isomerase (PPI)  catalyzes the elimination of folding intermediates with inappropriate disulfide cross-links

b) Protein disulfide isomerase (PDI) enzyme that catalyzes the interchange, or shuffling, of disulfide bonds until the bonds of the native conformation are formed

c) Peptide prolyl cis-trans isomerase (PPI) catalyzes the interconversion of the cis and trans isomers of Proline residue peptide bonds

d) Peptide prolyl isomerase (PPI) can be a fast step in the folding of proteins that contain some Pro peptide bonds in the cis conformation

Which of the following combinations is correct about protein folding pathways?

#Question id: 895

#Part-B Specialized Branches in Biotechnology

Which of the following is van’t Hoff plot equation?

#Question id: 896

#Part-B Specialized Branches in Biotechnology

van’t Hoff plot is drawn between