Positive Costimulatory Receptors: ICOS

ICOS binds to another member of the growing B7 family, ICOS-ligand (ICOS-L), which is also expressed on a subset of activated APCs.

ICOS plays a key role in maintaining the activity of already differentiated effector and memory T cells.

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Positive assortative mating refers to a tendency for like individuals to mate. For example, humans exhibit positive assortative mating for height.

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Inbreeding

Preferential mating between related individuals.

Inbreeding is more likely to take place in nature when population size becomes very small, and the number of mates is limited.

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#Section 3: Genetics, Cellular and Molecular Biology

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#Section 3: Genetics, Cellular and Molecular Biology

Inbreeding coefficient (F)

Probability that an individual has two identical alleles for a given gene.

Inbreeding coefficients can range from 0 to 1.