The heavy chain is then expressed on the cell surface in combination with the surrogate light chain, which is made up of VpreB and λ5. 

TLS Online TPP Program

#Id: 10364

#Section 2: General Biology

Properties of thymus-dependent and thymus-independent antigens

TLS Online TPP Program

#Id: 10365

#Section 2: General Biology

Antigen pieces are held within the binding groove of a cell surface protein called the major histocompatibility complex (MHC) molecule which recognized by T cell

TLS Online TPP Program

#Id: 10366

#Section 2: General Biology

Class I MHC, glycoproteins expressed on the surface of nearly all nucleated cells; the major function of the class I is presentation of endogenous peptide antigens to CD8+ T cells.

TLS Online TPP Program

#Id: 10367

#Section 2: General Biology

Daudi tumor cells, which are unable to synthesize β 2-microglobulin. 

TLS Online TPP Program

#Id: 10368

#Section 2: General Biology

Class II MHC glycoproteins expressed predominantly on pAPCs, where they primarily present exogenous antigenic peptides to CD4+ T cells.

TLS Online TPP Program

#Id: 10369

#Section 2: General Biology

Class III MHC genes encode several different proteins, some with immune functions, include the complement components C4, C2, and factor B, TNF-α and Lymphotoxin-α [TNF- α].