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Fingolimod—a Sphingosine-1-P Mimic Is an Oral Drug for Multiple Sclerosis

#Section 2: General Biology #Lipid #Part B Pointers
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#Section 3: Genetics, Cellular and Molecular Biology

Lysine acetylation & Detyrosylation are found only on α-tubulin and are absent from β-tubulin.

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#Section 3: Genetics, Cellular and Molecular Biology

Latrunculin, 
a toxin secreted by sponges, binds and sequesters G-actin

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#Id: 8202

#Section 3: Genetics, Cellular and Molecular Biology

Most of the lysosome membrane proteins, are highly glycosylated, which helps to protect them from the lysosome proteases

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#Id: 7928

#Section 3: Genetics, Cellular and Molecular Biology

Muscle cells have an abundant, modified smooth ER called the sarcoplasmic reticulum.

The release and reuptake of Ca2+ by the sarcoplasmic reticulum trigger myofibril contraction and relaxation, respectively

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#Section 3: Genetics, Cellular and Molecular Biology

Immediately after the entire precursor, Glc3Man9(GlcNAc)2 is transferred to a nascent polypeptide, three different enzymes, called  glycosidases, remove all three glucose residues and one particular mannose residue.



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