TLS Online TPP Program

#Id: 8602

#Section 3: Genetics, Cellular and Molecular Biology

cyclin-CDK complexes preferentially phosphorylate

serine and threonine residues when they are found within the consensus sequence:

[S/T]PX[R/K]K 

TLS Online TPP Program

#Id: 8600

#Section 3: Genetics, Cellular and Molecular Biology

R-factor 

In mammalian cells - cyclin D 

In yeast - Cln3

TLS Online TPP Program

#Id: 3772

#Section 1: Engineering Mathematics

Matter is anything that takes up space and has mass.

TLS Online TPP Program

#Id: 9162

#Section 3: Genetics, Cellular and Molecular Biology

A recessive allele (a) that causes a genetic disease has a frequency (q) of 0.01. If the population mates randomly (F = 0), the frequency of individuals affected by the disease (aa) will be q = 0.01 = 0.0001.

However, if F = 0.25 expected frequency of the aa is .0026.

TLS Online TPP Program

#Id: 8167

#Section 3: Genetics, Cellular and Molecular Biology

Most common CFTR mutation is a ΔF508 -

Prevents normal transport of CFTR to the plasma membrane by blocking its packaging into COPII vesicles budding from the ER. 

Change the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24.