A value of kLa = 30 h^-1 has been determined for a fermenter at its maximum practical agitator rotational speed and with air being sparged at 0.5 l gas/l reactor volume-min. E. coli with a qO2 of 10 mmol O2/g-dry wt-h are to be cultured. The critical dissolved oxygen concentration is 0.2 mg/l. The solubility of oxygen from air in the fermentation broth is 7.3 mg/l at 30⁰C.

What maximum concentration of E. coli can be sustained in this fermenter under aerobic conditions?

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#Question id: 27316

#Section 5: Bioprocess Engineering and Process Biotechnology

If the rate of product formation is approximately proportional to the rate of cell growth, then this pattern of product formation is referred to as:

TLS Online TPP Program

#Question id: 27317

#Section 5: Bioprocess Engineering and Process Biotechnology

In microbial cultivation, the expression for product synthesis rp = αµX + βX denotes

TLS Online TPP Program

#Question id: 27318

#Section 5: Bioprocess Engineering and Process Biotechnology

The specific productivity (qp) of an enzyme production is fitted linearly with specific growth rate (μ) of a fungal organism according to the equation qp = α.μ + β. The estimated values of constants α and β are 0.0006 and 25 respectively. The enzyme production kinetics is

TLS Online TPP Program

#Question id: 27319

#Section 5: Bioprocess Engineering and Process Biotechnology

Which one of the following statements is FALSE. Microbial secondary metabolites are

TLS Online TPP Program

#Question id: 27320

#Section 5: Bioprocess Engineering and Process Biotechnology

Two organisms A and B with the same µmax and Yx/s are cultivated independently in batch culture. They have Ks values of 1 g.l-1 and 3 g.l-1 respectively. Given that the initial substrate concentration was 5 g/l, which of the following is TRUE after complete exhaustion of the substrate?

TLS Online TPP Program

#Question id: 27321

#Section 5: Bioprocess Engineering and Process Biotechnology

An organism exhibits Monod growth with the following growth parameters, µm= 0.6 h-1 & Ks = 4 g/l. The specific growth rate, µ, of the organism at a substrate concentration of 2 g/l would be: