TLS Online TPP Program

#Question id: 3783


What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?

#Section 3: Genetics, Cellular and Molecular Biology
  1. The origins of replication occur only at the 5′ end.

  2. Helicases and single-strand binding proteins work at the 5′ end.

  3. DNA polymerase can join new nucleotides only to the 3′ end of a pre-existing strand, and the strands are antiparallel.

  4. DNA ligase works only in the 3′ → 5′ direction.

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TLS Online TPP Program

#Question id: 469

#Section 2: General Biology

The anaerobic conversion of 1 mol of glucose to 2 mol of lactate by fermentation is accompanied by a net gain of:

TLS Online TPP Program

#Question id: 532

#Section 4: Fundamentals of Biological Engineering

In glycolysis, fructose 1,6-bisphosphate is converted to two products with a standard free-energy change (DG'°) of 23.8 kJ/mol.  Under what conditions (encountered in a normal cell) will the free-energy change (DG) be negative, enabling the reaction to proceed to the right?

TLS Online TPP Program

#Question id: 533

#Section 4: Fundamentals of Biological Engineering

Glucose, labeled with 14C in different carbon atoms, is added to a crude extract of a tissue rich in the enzymes of the pentose phosphate pathway.  The most rapid production of 14CO2 will occur when the glucose is labeled in:

TLS Online TPP Program

#Question id: 535

#Section 4: Fundamentals of Biological Engineering

In some diabetic patients, glucose increases disproportionately and is unresponsive to an insulin challenge; under these conditions, how would oneʹs liver normally respond?

A) phosphorylating glucose for entry into the glycolytic pathway

B) saturating glucokinase with glucose

C) phosphorylating glucose for entry into the glycogen synthesis pathways

TLS Online TPP Program

#Question id: 538

#Section 4: Fundamentals of Biological Engineering

Which of the following statements are correct about cells that form ATP mainly by glycolysis are

A) anaerobic yeasts.

B) lactic acid bacteria.

C) kidney medulla cells.

TLS Online TPP Program

#Question id: 540

#Section 4: Fundamentals of Biological Engineering

During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD+ if glycolysis is to continue.  The most important reaction involved in the reoxidation of NADH is: