TLS Online TPP Program

#Question id: 15699


The PROSITE pattern representing the conserved sequence motif for a new family of AMP binding protein is [LIVMFY]-X(2)-[STG]-[STAG]-G-[ST]. You are given a sequence of a 15-amino acid stretch starting from the first residue of the motif. Which one of the following proteins is likely to have AMP binding function?

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology
  1. LIVMFYNGSTGSTAG
  2. MAGTAGSEGYIRHHC
  3. LIVMFYSTGSTAGGS
  4. LSSTAYTTSALKAAA
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TLS Online TPP Program

#Question id: 14105

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

The first secondary database developed was

TLS Online TPP Program

#Question id: 14116

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statements are CORRECT when a protein sequence database is searched using the BLAST algorithm? 
P. A larger E-value indicates higher sequence similarity 
Q. E-value < 10^-10 indicates sequence homology 
R. A higher BLAST score indicates higher sequence similarity 
S. E-value > 10^10 indicates sequence homology 

TLS Online TPP Program

#Question id: 3039

#Section 2: General Biology

An inoculated thioglycolate medium culture tube shows dense growth at the surface and turbidity throughout the rest of the tube. What is your conclusion?

TLS Online TPP Program

#Question id: 13054

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Precision will be reduced, but yield will be increased
Optimisation of a PCR reaction is often a compromise between the competing demands for precision, efficiency and yield. Although the specific effects may vary, generally, increasing the annealing temperature will increase non-specific primer binding and reduce precision. Increasing the length of the elongation phase will reduce the proportion of incomplete newly-synthesised strands and therefore increase yield. In this case, the potential effect on efficiency is unclear. Increasing the elongation phase would increase the reaction time, but the time taken to ramp down to a lower annealing temperature would be reduced.
What would the expected effect be on a PCR reaction if the primers used were slightly shorter and more variable than the intended oligonucleotide sequences?

TLS Online TPP Program

#Question id: 4803

#Section 3: Genetics, Cellular and Molecular Biology

Linked genes: