TLS Online TPP Program

#Question id: 36201


Which of the following statements is/are correct about PAM Matrix ? 

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology
  1. A PAM unit is defined as 1% amino acid change or one mutation per 100 residues.
  2. The increasing PAM numbers correlate with increasing PAM units and thus evolutionary distances of protein sequences.
  3. PAM250, which corresponds to 20% amino acid identity, represents 250 mutations per 100 residues.
  4. PAM matrices with lower serial numbers are more suitable for aligning more closely related sequences.