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The formation of many cell-cell adhesions entails two types of molecular interactions:
1.Trans binding interactions 
2. Cis binding interactions

#XL - T Zoology #Cell adhesion and roles of different adhesion molecules #Part B Pointers
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Loop method for inbreeding coefficient
Summation of all possible loop (1/2)n

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When inbreeding takes place, the frequency of genotype

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Close inbreeding is harmful because it increases the proportion of homozygotes and thereby boosts the probability that deleterious and lethal recessive alleles.

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