The heavy chain is then expressed on the cell surface in combination with the surrogate light chain, which is made up of VpreB and λ5. 

TLS Online TPP Program

#Id: 8655

#XL - R Botany

TLS Online TPP Program

#Id: 8656

#XL - R Botany

TLS Online TPP Program

#Id: 8846

#XL - R Botany

In budding yeast CKI p27 = Sic1 in metazoans

TLS Online TPP Program

#Id: 8847

#XL - R Botany

When CDK activity is low= helicases are loaded in G1

When CDK activity is high= helicases are activated in

S, G2 & M

TLS Online TPP Program

#Id: 8848

#XL - R Botany

TLS Online TPP Program

#Id: 8849

#XL - R Botany

Phosphorylation of MCM helicase activators by G1/S phase CDKs and S phase CDKs, prevents reloading of MCM helicases (ensuring that replication from each origin occurs only once during each cell cycle)