T1 cells are mIgMhi, mIgD -/lo, CD21-, CD23-, CD24+, and CD93+. 

T2 cells differ from T1 cells in having higher levels of mIgD and in expressing CD21 and CD23. 

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Effects of inbreeding on Japanese children

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Negative assortative mating refers to a tendency for unlike individuals to mate. people engaged in negative assortative mating for height.

Increases the frequency of heterozygous genotypes (Aa).

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Mutation

Mutation has changed the allelic frequency.

it increases genetic variation within populations and between population.

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