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TLS Online TPP Program

#Id: 2211


Darwin’s evolutionary theory- Evolution as such is the simple proposition that the characteristics of organisms change over time.

#XL - T Zoology #Lamarck; Darwin–concepts of Variation #Part B Pointers
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TLS Online TPP Program

#Id: 9467

#XL - T Zoology

SH2 domain of STAT binds to a specific phosphotyrosine in the cytosolic domain of an activated receptor

TLS Online TPP Program

#Id: 9468

#XL - T Zoology

Erythropoietin receptor & the receptors for GH, prolactin, G-CSF, activates STAT5 but not STATs 1, 2, 3, or 4. 

TLS Online TPP Program

#Id: 9469

#XL - T Zoology

IL-2 receptor complex activates
STATs 1, 3, and 5 but not STATs 2 or 4

TLS Online TPP Program

#Id: 9470

#XL - T Zoology

Phosphorylated STAT dissociates spontaneously from the receptor, and two phosphorylated STAT proteins form a homodimer.

TLS Online TPP Program

#Id: 9471

#XL - T Zoology

STAT5 becomes activated in erythroid progenitor cells and induces expression of the protein Bcl-xL.

TLS Online TPP Program

#Id: 9472

#XL - T Zoology

Two mechanisms for terminating cytokine signaling:
1. Short-term regulation: SHP1
2. Long-term regulation: SOCS proteins

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