TLS Online TPP Program

#Id: 7914

#XL - Q Biochemistry

Matrix-targeting sequences

Located at the N-terminus

Usually 20–50 amino acids in length

Rich in hydrophobic amino acids, positively charged basic amino acids (arginine & lysine), and hydroxylated ones (serine and threonine)

Amphipathicity of matrix-targeting sequences is critical to their function

TLS Online TPP Program

#Id: 10753

#XL - R Botany

Thyrsus

“Racemes of cymes”

Lateral pedicillate 

Ex- Ocimum, Anisomeles (Sweet basils

TLS Online TPP Program

#Id: 9340

#XL - T Zoology

N-terminal prodomain is required for proper folding and dimerization of the C-terminal TGF-β domain.

TLS Online TPP Program

#Id: 8357

#XL - Q Biochemistry

VASP 

has a proline-rich

hold onto the end of the newly formed filament

protect the end of the growing filament from CapZ

TLS Online TPP Program

#Id: 7911

#XL - Q Biochemistry

MCSs also serve as interfaces for the transfer of ions (Ca+2 ) and small molecules (glycerophospholipids) between the ER and mitochondria.