In healthy mitochondria, PINK1 resides in the mitochondrial matrix.

In damaged or dysfunctional mitochondria, PINK1 resides on the outer mitochondrial membrane, where it recruits cytosolic Parkin.

TLS Online TPP Program

#Id: 7908

#XL - Q Biochemistry

In healthy mitochondria, PINK1 resides in the mitochondrial matrix.

In damaged or dysfunctional mitochondria, PINK1 resides on the outer mitochondrial membrane, where it recruits cytosolic Parkin.

TLS Online TPP Program

#Id: 10095

#XL - T Zoology

Hemidesmosomes are integrin-containing anchoring junctions that attach cells to elements of the underlying extracellular matrix.

TLS Online TPP Program

#Id: 10096

#XL - T Zoology

Integrins have an important function in neuroregeneration after injury of the peripheral nervous system.

TLS Online TPP Program

#Id: 10097

#XL - T Zoology

Three major classes of animal-cell junctions: 

1. Anchoring junctions

2. Tight junctions

3. Gap junctions

TLS Online TPP Program

#Id: 10098

#XL - T Zoology

Adherens junctions 

Adhesion type- Cell-cell

Principal CAMs- Cadherins

Cytoskeletal attachment- Actin filament

TLS Online TPP Program

#Id: 10099

#XL - T Zoology

Adherens junctions

functions as a tension cable that can internally brace the cell and thereby control its shape

TLS Online TPP Program

#Id: 10100

#XL - T Zoology

Desmosomes

Adhesion type- Cell-cell

Cytoskeletal attachment- Intermediate filaments