The presence of one or more fatty acids with cis double bonds interferes with this tight packing and results in less stable aggregates.

TLS Online TPP Program

#Id: 8088

#XL - T Zoology

The presence of one or more fatty acids with cis double bonds interferes with this tight packing and results in less stable aggregates.

TLS Online TPP Program

#Id: 8525

#XL - Q Biochemistry

Detyrosylated microtubules are more stable, because they are more resistant to depolymerization by kinesin-13 and related proteins.

TLS Online TPP Program

#Id: 8524

#XL - Q Biochemistry

Detyrosylation 

tyrosine can be removed by a carboxypeptidase, where it sequentially removes the C-terminal tyrosines from α-tubulin subunits. 

TLS Online TPP Program

#Id: 8523

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 8522

#XL - Q Biochemistry

Lysine acetylation 

ε-amino group of a specific lysine of α-tubulin

Microtubules are stabilized against breakage (centrioles, basal bodies, & primary cilia)

TLS Online TPP Program

#Id: 8521

#XL - Q Biochemistry

Lysine acetylation & Detyrosylation are found only on α-tubulin and are absent from β-tubulin.

TLS Online TPP Program

#Id: 8520

#XL - Q Biochemistry

Post-translational modifications of tubulin:

Lysine acetylation

Detyrosylation

Polyglutamylation

Polyglycylation