Most common CFTR mutation is a ΔF508 -

Prevents normal transport of CFTR to the plasma membrane by blocking its packaging into COPII vesicles budding from the ER. 

Change the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24.

TLS Online TPP Program

#Id: 8167

#XL - Q Biochemistry

Most common CFTR mutation is a ΔF508 -

Prevents normal transport of CFTR to the plasma membrane by blocking its packaging into COPII vesicles budding from the ER. 

Change the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24.

TLS Online TPP Program

#Id: 7839

#XL - T Zoology

TLS Online TPP Program

#Id: 7838

#XL - T Zoology

For monosaccharides with two or more asymmetric carbons, the prefix d or l refers to the configuration of the highest numbered asymmetric carbon (the asymmetric carbon farthest from the carbonyl carbon).

TLS Online TPP Program

#Id: 7836

#XL - T Zoology

A carbon atom with four different substituents is said to be asymmetric, and asymmetric carbons are called chiral centers

Chiral carbon most distant from the carbonyl carbon has the same configuration as the chiral carbon in D-glyceraldehyde.

TLS Online TPP Program

#Id: 7835

#XL - T Zoology

Aldoses with at least three carbons and ketoses with at least four carbons contain chiral centers

TLS Online TPP Program

#Id: 7995

#XL - T Zoology

The habitat of an organism is the place, or physical setting, in which it lives.

TLS Online TPP Program

#Id: 7996

#XL - T Zoology

An organism’s niche includes the range of abiotic and biotic conditions it can tolerate. 

In the case of the cottontail rabbit, its niche includes the ranges of temperature and humidity that it can tolerate, the plants that it eats, and the predatory hawks and coyotes with which it coexists.