The major NPF family is characterized by the presence of a region called WCA (WH2, connector, acidic)

TLS Online TPP Program

#Id: 10103

#XL - T Zoology

Hemidesmosomes

Adhesion type- Cell-matrix

Cytoskeletal attachment- Intermediate filaments

TLS Online TPP Program

#Id: 10104

#XL - T Zoology

The principal ECM adhesion receptor in epithelial hemidesmosomes is integrin α6β4.

TLS Online TPP Program

#Id: 10105

#XL - T Zoology

Hemidesmosomes

Function- Shape, rigidity, signaling

TLS Online TPP Program

#Id: 10106

#XL - T Zoology

Focal adhesions 

Adhesion type- Cell-matrix

Adhesion receptors- Integrins

Cytoskeletal attachment- Actin filaments

TLS Online TPP Program

#Id: 10107

#XL - T Zoology

Focal adhesion

Function- Shape, signaling, force transmission, cell movement

TLS Online TPP Program

#Id: 10108

#XL - T Zoology

Tight junctions seal off body cavities and restrict diffusion of membrane components