When E2Fs are bound to Rb, not only are they transcriptionally inactive, but they also function to repress transcription by recruiting chromatin-modifying enzymes that promote deacetylation and methylation of specific histone lysines.

TLS Online TPP Program

#Id: 9957

#XL - T Zoology

Wnts are paracrine factors that make up a large family of cysteine-rich glycoproteins

TLS Online TPP Program

#Id: 9506

#XL - R Botany

P. syringae pv. Syringae (Pss) secrete syringolin A (SylA), a peptide derivative synthesized by a mixed nonribosomal peptide synthetase/polyketide synthetase encoded by a gene cluster. 

TLS Online TPP Program

#Id: 8937

#XL - T Zoology

Phosphorylated Knl1 binds the checkpoint protein kinase Bub1-Bub3 and checkpoint protein BubR1. These three proteins, recruit the Mad1-Mad2 complex to the kinetochore.

TLS Online TPP Program

#Id: 10804

#XL - R Botany

phytoalexins, antimicrobial compounds synthesized in response to bacterial or fungal infection that help limit the spread of the invading pathogen.

TLS Online TPP Program

#Id: 8913

#XL - T Zoology

APC/CCdc²⁰ is inhibited by a checkpoint pathway that ensures that anaphase is not initiated until all chromosomes have achieved proper attachment to the mitotic apparatus.