Rb protein regulation by G1 CDKs in mammalian cells is analogous to Whi5 regulation by Cln3-CDK in yeast.

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Rb protein regulation by G1 CDKs in mammalian cells is analogous to Whi5 regulation by Cln3-CDK in yeast.

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Amount of change in allele frequency as a result of mutation equals the mutation rate times the allelic frequency

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The overall change in allelic frequency is a balance between the opposing forces of forward mutation and reverse  mutation:

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Determining allelic frequencies at equilibrium

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Migration

Change in the allelic frequencies is the influx of genes from other populations, commonly called migration or gene flow