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TLS Online TPP Program

#Id: 8879

This combination of two positive feedback loops:
one that activates a CDK1 activator (Cdc25C)
one that inhibits a CDK1 inhibitor (Wee1)
results in the abrupt and irreversible transition from G2 into mitosis.

#XL - R Botany #Steps in cell cycle, regulation and control of cell cycle #Part B Pointers
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TLS Online TPP Program

#Id: 8879

#XL - T Zoology

This combination of two positive feedback loops:
one that activates a CDK1 activator (Cdc25C)
one that inhibits a CDK1 inhibitor (Wee1)
results in the abrupt and irreversible transition from G2 into mitosis.
TLS Online TPP Program

#Id: 8655

#XL - R Botany
TLS Online TPP Program

#Id: 8656

#XL - R Botany
TLS Online TPP Program

#Id: 8846

#XL - R Botany

In budding yeast CKI p27 = Sic1 in metazoans
TLS Online TPP Program

#Id: 8847

#XL - R Botany

When CDK activity is low= helicases are loaded in G1
When CDK activity is high= helicases are activated in
S, G2 & M
TLS Online TPP Program

#Id: 8848

#XL - R Botany
TLS Online TPP Program

#Id: 8849

#XL - R Botany

Phosphorylation of MCM helicase activators by G1/S phase CDKs and S phase CDKs, prevents reloading of MCM helicases (ensuring that replication from each origin occurs only once during each cell cycle)