Phosphorylated Knl1 binds the checkpoint protein kinase Bub1-Bub3 and checkpoint protein BubR1. These three proteins, recruit the Mad1-Mad2 complex to the kinetochore.

TLS Online TPP Program

#Id: 9881

#XL - T Zoology

Defensins and cathelicidin LL-37 are secreted constitutively by epithelial cells in many tissues, and are stored as well in neutrophil granules, where they contribute to killing phagocytosed microbes.

TLS Online TPP Program

#Id: 9882

#XL - T Zoology

Cellular innate immune responses

TLS Online TPP Program

#Id: 9883

#XL - T Zoology

Phagocytosis

TLS Online TPP Program

#Id: 9884

#XL - T Zoology

TLS Online TPP Program

#Id: 9885

#XL - T Zoology

Processes That Kill Phagocytosed Microbes

Agents include antimicrobial proteins and peptides, low pH, hydrolytic enzymes including lysozyme and proteases activated by the increasing acidity of the phagolysosomes, and specialized molecules that mediate oxidative attack.

TLS Online TPP Program

#Id: 9886

#XL - T Zoology

Chronic granulomatous disease (CGD)- NADPH oxidase mutate