Cardiolipin

an unusual “double” phospholipid containing four fatty acid chains

found primarily in the inner mitochondrial membrane

acts to improve the efficiency of oxidative phosphorylation, by restricting proton flow across the membrane

TLS Online TPP Program

#Id: 7924

#XL - Q Biochemistry

Cardiolipin

an unusual “double” phospholipid containing four fatty acid chains

found primarily in the inner mitochondrial membrane

acts to improve the efficiency of oxidative phosphorylation, by restricting proton flow across the membrane

TLS Online TPP Program

#Id: 8518

#XL - Q Biochemistry

Defects in LIS1 

Miller-Dieker lissencephaly

means “smooth brain”

TLS Online TPP Program

#Id: 8517

#XL - Q Biochemistry

Other proteins function with dynein & involved in regulating the activity of dynein during brain development:

LIS1 and NudE

TLS Online TPP Program

#Id: 8516

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 8515

#XL - Q Biochemistry

Kinesin-1 

is regulated by a 

head-to-tail interaction

TLS Online TPP Program

#Id: 8514

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 8415

#XL - Q Biochemistry

Dilated cardiomyopathy

Minor missense mutations in the cardiac actin gene