For most, but not all, RTKs, the weakly active kinase in each subunit is phosphorylate a key tyrosine in the activation loop of the other subunit (trans-phosphorylation)

TLS Online TPP Program

#Id: 9895

#XL - T Zoology

TLS Online TPP Program

#Id: 9896

#XL - T Zoology

TLS Online TPP Program

#Id: 9897

#XL - T Zoology

C-type lectin receptor (CLR)

CLRs are plasma membrane receptors and generally recognize carbohydrate components of fungi, mycobacteria, viruses, parasites, and some allergens.

TLS Online TPP Program

#Id: 9898

#XL - T Zoology

Retinoic acid-inducible gene-I-like receptors (RLRs) are soluble PRRs that reside in the cytosol of many cell types.

TLS Online TPP Program

#Id: 9899

#XL - T Zoology

The three known RLRs (RIG-I, MDA5, and LGP2) are CARD-containing RNA helicases that recognize viral RNAs, usually from RNA viruses such as influenza, measles, and West Nile.

TLS Online TPP Program

#Id: 9900

#XL - T Zoology

Nod-like receptors

The NLRs are a large family of cytosolic proteins activated by intracellular PAMPs