In the absence of insulin, the extracellular domain adopts a symmetric inverted U-shaped conformation. 

TLS Online TPP Program

#Id: 8141

#XL - Q Biochemistry

Anterograde transport through the golgi occurs by cisternal maturation

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#Id: 8142

#XL - Q Biochemistry

Retrograde transport

COPI vesicles = cis-Golgi to ER

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#Id: 8143

#XL - Q Biochemistry

Vesicle Type- COPII

Transport - ER to cis-Golgi 

Coat Proteins - Sec23/Sec24 and Sec13/Sec31, Sec16

Associated GTPase- Sar1

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#Id: 8144

#XL - Q Biochemistry

Vesicle Type- COPI

Transport - cis-Golgi to ER

Coat Proteins – Coatomers

Associated GTPase- ARF

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#Id: 8145

#XL - Q Biochemistry

Vesicle Type- Clathrin

Transport - trans-Golgi to endosome

Coat Proteins – Clathrin + AP1 complexes

                            Clathrin + GGA

Associated GTPase- ARF

TLS Online TPP Program

#Id: 8146

#XL - Q Biochemistry