Kinase domains typically contain two regions:

N and C lobes

TLS Online TPP Program

#Id: 8640

#XL - R Botany

In vertebrates, Rb is the major guardian of the cell cycle, integrating information about DNA damage and cell growth

TLS Online TPP Program

#Id: 9333

#XL - T Zoology

An evolutionarily conserved family of receptor serine kinases - TGF-β receptor family

TLS Online TPP Program

#Id: 9645

#XL - T Zoology

Active Ras⋅GTP binds to the N-terminal autoinhibitory domain of Raf, altering its conformation and allowing the phosphate attached to this domain to be removed by cytosolic phosphatases, causing loss of 14-3-3 binding.

TLS Online TPP Program

#Id: 9529

#XL - R Botany

Plant viruses have small genomes; most encode only three to 10 proteins.

TLS Online TPP Program

#Id: 4919

#XL - Q Biochemistry

Secondary plots for competitive inhibition.