Active Ras⋅GTP binds to the N-terminal autoinhibitory domain of Raf, altering its conformation and allowing the phosphate attached to this domain to be removed by cytosolic phosphatases, causing loss of 14-3-3 binding.

TLS Online TPP Program

#Id: 8391

#XL - Q Biochemistry

When the Ca2+ level rises, Ca2+ binds CaM.

TLS Online TPP Program

#Id: 9265

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 9655

#XL - T Zoology

Feedback regulation by MAP Kinase

Phosphorylation of threonine residue in HER1 decreases the ability of the receptor kinase to become fully active.

TLS Online TPP Program

#Id: 8515

#XL - Q Biochemistry

Kinesin-1 

is regulated by a 

head-to-tail interaction

TLS Online TPP Program

#Id: 9150

#XL - T Zoology

Positive assortative mating refers to a tendency for like individuals to mate. For example, humans exhibit positive assortative mating for height.