Active Ras⋅GTP binds to the N-terminal autoinhibitory domain of Raf, altering its conformation and allowing the phosphate attached to this domain to be removed by cytosolic phosphatases, causing loss of 14-3-3 binding.

TLS Online TPP Program

#Id: 8100

#XL - T Zoology

Sphingolipids contain a single fatty acid, in amide linkage to the sphingosine backbone.

TLS Online TPP Program

#Id: 8099

#XL - T Zoology

TLS Online TPP Program

#Id: 8098

#XL - T Zoology

The surfaces of the cells that form the alveoli (small air spaces of the lung) are coated with surfactant, which decreases the alveolar surface tension. 

Lung surfactant contains 80 to 90% phospholipid by weight, and 70 to 80% of the phospholipid is phosphatidylcholine, mostly the dipalmitoyl species.

TLS Online TPP Program

#Id: 8097

#XL - T Zoology

Dipalmitoylphosphatidylcholine (DPPC) is the major lipid of lung surfactant, the protein–lipid mixture that is essential for normal pulmonary function.

TLS Online TPP Program

#Id: 8096

#XL - T Zoology

TLS Online TPP Program

#Id: 8095

#XL - T Zoology

Platelet-activating factor released from basophils and stimulates platelet aggregation and the release of vasoconstrictor serotonin from platelets.