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Processes That Kill Phagocytosed Microbes
Agents include antimicrobial proteins and peptides, low pH, hydrolytic enzymes including lysozyme and proteases activated by the increasing acidity of the phagolysosomes, and specialized molecules that mediate oxidative attack.

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TLS Online TPP Program

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Rb protein regulation by G1 CDKs in mammalian cells is analogous to Whi5 regulation by Cln3-CDK in yeast.

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One of the important substrates of the G1/S phase cyclin-CDK complexes is Cdh1.

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During exit from mitosis and G1, 
Cdh1 is de-phosphorylated and APC/Ccdh1 is active.

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During S phase and mitosis, 
Cdh1 is phosphorylated, Cdh1 dissociates from APC/C, and APC/C becomes inactive.

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G1/S phase CDKs phosphorylate Cdh1 at the 
G1-S phase transition

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