Wnt ligands are recognized by Frizzled/retinoic acid-related orphan receptor (ROR)/receptor tyrosine kinase (RYK) receptor complexes

TLS Online TPP Program

#Id: 8195

#XL - Q Biochemistry

A Pex 2, Pex 10, and Pex 12 complex embedded in the peroxisomal membrane transfers Ubiquitin to two embedded Pex 5 receptors.

TLS Online TPP Program

#Id: 10291

#XL - Q Biochemistry

The second phase of T-cell development

1.Positive selection: Selection for those cells whose T-cell receptors engage self-MHC.

2.Negative selection: Selection against those cells whose T-cell receptors bind too strongly to self-peptide/MHC combinations.

3.Lineage commitment: Commitment of thymocytes to effector cell lineages, including CD4 helper or CD8 cytotoxic populations

TLS Online TPP Program

#Id: 8625

#XL - T Zoology

Human SCF complexes contain: 

Three core components - Cul1 subunit, RBX1, Skp1 

and a substrate-targeting F-box protein

TLS Online TPP Program

#Id: 8888

#XL - R Botany

A key function of mitotic CDKs, together with other protein kinases and ubiquitin-protein ligases, is to induce the formation of the mitotic spindle, also known as the mitotic apparatus.

TLS Online TPP Program

#Id: 9378

#XL - T Zoology

Learned behaviors - which are genetically hardwired and can be performed without any prior experience or training.