Following statements are regarding to the formins which involve in filament assembly.

A. All formin family members have two adjacent domains in common, the so called FH1 and FH2 domains (formin-homology domains 1 and 2).

B. Two FH2 domains from two individual formin monomers associate to form a doughnut-shaped complex can form a dimer and nucleate filament assembly.

C. The FH1 domain of formin is rich in proline residues, which serve as sites for the binding of several profilin molecules.

D. The FH2 domain behaves as a landing site for profilin–ATP–G-actin to increase the local concentration of these complexes.

E. Formins are activated by membrane bound Rho-GTP, a Ras-related small GTPase.

Which of the following combination is correct?

#Question id: 5290

#Unit 8. Inheritance Biology

The following table shows mapping data from three interrupted mating experiments using three different Hfr strains and an F- strain: The order of genes is

#Question id: 5289

#Unit 8. Inheritance Biology

A donor strain of bacteria with genes a+b+c+ is infected with phages to map the donor chromosome with transduction. The phage lysate from the bacterial cells is collected and used to infect a second strain of bacteria that are a_ b_ c_.

Based on the above, which one of the following conclusions is correct?

#Question id: 5288

#Unit 8. Inheritance Biology

Donor strain of bacteria with His+ Ara+ Met+ Leu+ Cys+ Lys+ is infected with phages to map the donor chromosome with generalized transduction .The Phage lysate from bacterial cell is collected and use to infect second strain of bacteria that are His- Ara- Met- Leu- Cys- Lys- . Different transducing phages are selected on using different minimal media and their presence of growth (+) and absence of growth (-) given in table

Which of the following is correct order of gene?

#Question id: 5287

#Unit 8. Inheritance Biology

Interrupted matting of different Hfr strain with F- E.coli cell resulting generation of following strain  Order of gene is

#Question id: 5286

#Unit 8. Inheritance Biology

An Hfr strain with genotype A B C D (each gene for amino acid synthesis )and that transfers the A gene very late was mated with recipient strain with genotype a b c d. After mating for several hours, the mixture was diluted and plated on minimal media with four different supplements having various number of colony

Media supplement with amino acid  

                 Colony                                          number

                  A+C                                                 500

                  C+D                                                  50

                     B                                                    10

                     A                                                   250

What is order of gene

#Question id: 5285

#Unit 8. Inheritance Biology

A transformation experiment is carried out using donor DNA that is A+B+C+ and a recipient that is A-B- C-. A+ transformants are selected and tested further. Of these, 64% are B+ and none are C+. Also, B+ are selected, and 8% are also C+. What is the gene order