Following statements are regarding to the Surveillance mechanisms in cell cycle regulation.

A. Surveillance mechanisms known as checkpoint pathways establish dependencies among cell cycle events and ensure that the next cell cycle event does not occur prior to the completion of a preceding event.

B. In response to DNA damage, two related protein kinases, ATM and ATR, are recruited to the site of the damage, where they activate signaling pathways that lead to cell cycle arrest, repair, and under some circumstances, apoptosis.

C. The spindle assembly checkpoint pathway, which causes initiation of anaphase, utilizes Mad2 and other proteins to regulate APC/CCdc20, which targets securing and mitotic cyclins for ubiquitinylation.

D. The spindle position checkpoint pathway prevents mitotic CDK inactivation when the spindle is mispositioned. In this pathway, localized activators and inhibitors and a sensor that shuttles between them allow cells to sense spindle position.

Which of the following statement is incorrect?

TLS Online TPP Program

#Question id: 23641

#General Aptitude

A class starts after lunch at 1.00p.m. and lasts till 3.52 p.m. In this duration four periods are held. Before every period 4 minutes are allowed for going from one room to another. What is the exact duration for each period?

TLS Online TPP Program

#Question id: 23640

#General Aptitude

I was quite alone in the park. After some time an old man and an old woman came there. After them two couples with a baby came there. Now, how many persons are there?

TLS Online TPP Program

#Question id: 23639

#General Aptitude

There are three pillars X, Y and Z of different heights. There spiders A, B and C start of climb on these pillars simultaneously. In one chance A climbs on X by 5 cm but slips down 1 cm. B climbs on Y 6 cm but slips down 3 cm. C climbs on Z 7 cm but slips down 2 cm. If they each requires 50 chances to reach the top of the pillar, what is the height of the shortest pillar?

TLS Online TPP Program

#Question id: 23638

#General Aptitude

The minimum number of colours required to paint all the sides of a cube so that no two adjacent faces may have the same colour, is

TLS Online TPP Program

#Question id: 23637

#General Aptitude

How many numbers from 1 to 100 are such each which is divisible by 8 and whose at least one digit is 8?

TLS Online TPP Program

#Question id: 23636

#General Aptitude

A, B, C, D and E distribute some cards among themselves in a manner that A gets one less than B; C gets 5 more than D; E gets 3 more than B while D gets as many as b. who gets the least number of cards?