Find correct order of cotranslational translocation in endoplasmic reticulum

A. Transfer of the nascent polypeptide–ribosome to the translocon leads to opening of this

translocation channel to admit the growing polypeptide adjacent to the signal sequence, which is transferred to a hydrophobic binding site next to the central pore. Both the SRP and SRP receptor, once dissociated from the translocon, hydrolyze their bound GTP and then are ready to initiate the insertion of another polypeptide chain.

B. As the polypeptide chain elongates, it passes through the translocon channel into the ER lumen, where the signal sequence is cleaved by signal peptidase and is rapidly degraded.

C. The SRP and the nascent polypeptide chain–ribosome complex bind to the SRP receptor in

the ER membrane. This interaction is strengthened by the binding of GTP to both the SRP and its receptor.

D. The ER signal sequence emerges from the ribosome; it is bound by a signal recognition particle (SRP).

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#Question id: 7763

#Unit 5. Developmental Biology

Two major sources of mutation are radiation and reactive oxygen species (ROS).The reactive oxygen species hypothesis for aging postulates that 

1) Senescence results from the accumulation of DNA, lipid, and protein damage inflicted by ROS of mitochondrial origin; and

2) Mitochondria of long-lived species should produce high ROS than do mitochondria of short-lived species.

3) the capacity of mitochondria to consume ROS might distinguish long-lived species from short-lived species, rather than differences in ROS generation. 

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#Question id: 13165

#Unit 5. Developmental Biology

One of the main ways by which the insulin signaling pathway might function to lower longevity is to activate mTORC1, a protein kinase complex that promotes the translation of mRNA into proteins in response to nutrients and hormones, select incorrect statement;

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#Question id: 7286

#Unit 5. Developmental Biology

Which of the floral whorls is affected in apetala 3/pistillata (ap3/pi) mutants?

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#Question id: 7305

#Unit 5. Developmental Biology

In plants, a growing mass of unorganized and undifferentiated cells that cover a wound; these cells can be induced to form a plant meristem and develop into shoots and/or roots called as

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#Question id: 7307

#Unit 5. Developmental Biology

Which of the following statements regarding flowering plants is correct?

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#Question id: 7310

#Unit 5. Developmental Biology

Which statement best describes the mechanism for circadian rhythm?