Following statements are regarding to the phosphoinositide signaling pathway.

A. Many RTKs and cytokine receptors can initiate the IP3/ DAG signaling pathway by activating phospholipase Cβ (PLCβ), a different PLC isoform.

B. Activated RTKs and cytokine receptors also can initiate another phosphoinositide pathway by binding a PI-3 kinase, thereby allowing the enzyme access to its membrane-bound phosphoinositide substrates, which then become phosphorylated at the 3 position.

C. Protein kinase B (PKB) becomes partially activated by binding to PI 3-phosphates with its PH domain.

D. Full activation of PKB requires phosphorylation by the kinase PDK1, which is also recruited to the membrane by binding to PI 3-kinase, and by a second kinase, PDK2.

Which of the following combination is incorrect?

TLS Online TPP Program

#Question id: 10772

#Unit 8. Inheritance Biology

In an experiment plant RR round genotype have 100 seeds. In F1 generation 70 seeds are round and 30 seeds are wrinkled. So what will be

the penetrance value for round seeds?

TLS Online TPP Program

#Question id: 10771

#Unit 8. Inheritance Biology

What is penetrance?

A- % of individuals having phenotype according to their genotype.

B- Penetrance refers to the likelihood that a clinical condition will occur when a particular genotype is absent.

C- 100% expressivity always gives 100% penetrance.

which one of the correct combination-

TLS Online TPP Program

#Question id: 10769

#Unit 8. Inheritance Biology

In merabilis jalapa plant red plant RR Cross with white plant rr. In F1 generation the phenotype obtained was Rr Pink. Which type of cross it is

TLS Online TPP Program

#Question id: 10768

#Unit 8. Inheritance Biology

Dihybrid test cross genotypic and phenotypic ratio is

TLS Online TPP Program

#Question id: 10767

#Unit 8. Inheritance Biology

Chi square test is used to verify

TLS Online TPP Program

#Question id: 10766

#Unit 8. Inheritance Biology

what is degree of freedom

1- Degrees of freedom represent the number of ways in which the observed outcome categories are free to vary.

2- Degree of freedom refers to the minimum number of logically independent values, which are values that have the freedom to vary in the data sample.

3.Degrees of freedom represent the number of ways in which the observed outcome categories are restrict to vary.

Which one are correct statement?