TLS Online TPP Program

#Question id: 5313


Which of the following statements correctly describes one of the characteristics of alternative splicing in vertebrate genomes?

#Unit 11. Evolution and Behavior
  1. Vertebrate genomes can produce more than one polypeptide from a single gene.

  2. Vertebrate genomes can produce only one polypeptide from a single gene.

  3. Vertebrate genomes are always smaller than other organisms.

  4. Alternative splicing leaves introns in vertebrate genes after they are transcribed.

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TLS Online TPP Program

#Question id: 4828

#Unit 8. Inheritance Biology

Consider two pairs of alleles, G/g and H/h, that follow complete dominance inheritance. The initial cross consisted of GG hh males and gg HH females, and the F I female progeny were test crossed with gg hh males to produce 380 Gghh progeny out of 1000 total progeny. What is approximate distance between Gene G and H.

TLS Online TPP Program

#Question id: 12975

#Unit 10. Ecological Principles

Which of the following is true with respect to oligotrophic lakes and eutrophic lakes?

TLS Online TPP Program

#Question id: 10308

#Unit 6. System Physiology – Plant

Oxidative decarboxylation of pyruvate to acetyl-CoA by the PDH complex, how the pyruvate dehydrogenase complex carries out the five consecutive reactions in the decarboxylation and dehydrogenation of pyruvate?

 A) Pyruvate reacts with the bound thiamine pyrophosphate (TPP) of pyruvate dehydrogenase, undergoing decarboxylation to the hydroxyethyl derivative

 B) A transesterification in which the —SH group of CoA replaces the —SH group of E2 to yield acetyl-CoA and the fully reduced (dithiol) form of the lipoyl group

 C) The reduced FADH2 of E3 transfers a hydride ion to NAD1 , forming NADH, the enzyme complex is now ready for another catalytic cycle

 D) The transfer of two electrons and the acetyl group from TPP to the oxidized form of the lipoyllysyl group of the core enzyme, dihydrolipoyl transacetylase, to form the acetyl thioester of the reduced lipoyl group

 E) Dihydrolipoyl dehydrogenase promotes transfer of two hydrogen atoms from the reduced lipoyl groups of E2 to the FAD prosthetic group of E3 , restoring the oxidized form of the lipoyllysyl group of E2

 Find out the correct sequence of action of this complex enzyme?

TLS Online TPP Program

#Question id: 890

#Unit 1. Molecules and their Interaction Relevant to Biology

Some of the misfolded protein or defective Protein causes disease as follows;

               Disease                                             Defective Protein

A)  Parkinson’s disease                                  i) Amyloid-β protein

B)  Alzheimer’s disease                                  ii) Superoxide dismutase

C) Huntington’s disease                                iii) Lysozyme

D) Lysozyme amyloidosis                             iv) α-Synuclein

E) Amyotrophic lateral sclerosis                   v) polyglutamate expansion

Match the correct disease with its misfolded proteins;

TLS Online TPP Program

#Question id: 10975

#Unit 7. System Physiology – Animal

A teenaged boy with numerous nosebleeds was referred to a physician for evaluation prior to a minor surgery. His prothrombin time (PT) was 11 sec (11–15 sec normal), partial thromboplastin time (PTT) was 58 sec (25–40 sec normal), and bleeding time was 6.5 min (2–7 min normal). Which of the following is most likely abnormal in this young man?