In a typical Mendelian population, individuals carrying gene ‘a’ in homozygous condition suffer from phenylketonurea. Those with A in homozygous condition are normal. Others, who are heterozygotic with Aa, are carriers. If the frequency of ‘a’ in a population is 0.20, what is the percentage of normal individual in the population?

#Question id: 311

#SCPH28 | Zoology

Which of the following has no contribution to the stability of tRNA?

#Question id: 634

#SCPH05 I Biotechnology

An enzyme has a Vmax of 50 micromol product formed (minute x mg protein)-1 and a Km of 10 microM for the substrate. When a reaction mixture contains the enzyme and 5 microM substrate, which of the following percentages of the maximum velocity will be closest to the initial reaction rate?

#Question id: 2986

#SCPH06 I Botany

During ubiquitin-mediated protein degradation in various events of cell cycle, ubiquitin-protein ligases ubiquitinylate substrate proteins, marking them for degradation by proteasomes. Cyclins are degraded through the action of two different ubiquitin-protein ligases, SCF and the anaphase-promoting complex or cyclosome. Following statements are regarding to SCF and APC/C.

A. SCF controls the G1–S phase transition by degrading G1/S phase cyclins and, CDK inhibitory proteins.

B. APC/C degrades S phase and mitotic cyclins, thereby promoting the exit from mitosis.

C. SCF and APC/C are multi-subunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases.

D. SCF and APC/C belong to the different ubiquitin-protein ligase family, their regulation is same.

E. SCF recognizes its substrates only when they are phosphorylated.

F. SCF and APC/C both recognizes its substrates only when they are phosphorylated.

Which of the following is incorrect?

#Question id: 16323

#I Life Science/ Life Sciences Group – I-V

#Question id: 12754

#SCPH28 | Zoology