Nurturing Life Sciences
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Adherens junctions
functions as a tension cable that can internally brace the cell and thereby control its shape
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#Unit 7. System Physiology – Animal
Thyroid stimulating hormone induces both NIS expression and the retention of NIS in the basolateral membrane.
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Iodide is transported out of the thyroid cells across the apical membrane into the follicle by a chloride-iodide ion counter- transporter molecule called pendrin.
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Thyroglobulin is a glycoprotein contains 123 tyrosine residues, but only 4–8 of these are normally incorporated into thyroid hormones.
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Oxidation of iodine is mediated by thyroid peroxidase, a membrane-bound enzyme found in the thyrocyte apical membrane.
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When the peroxidase system is blocked or when it is hereditarily absent from the cells, the rate of formation of thyroid hormones falls to zero
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“Organification” of Thyroglobulin- Iodination of tyrosine and formation of the thyroid hormones