Nurturing Life Sciences
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Comb shapes in chickens
9/16 walnut (R- P-)
3/16 rose (R- pp)
3/16 pea (rr P-)
1/16 single (rr pp)
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#Unit 3. Fundamental Processes
Mutations are also caused by compounds that substitute for normal bases (base analogs) or slip between the bases (intercalating agents) to cause errors in replication.
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One of the most mutagenic base analogs is 5-bromouracil, an analog of thymine.
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The presence of the bromo substituent allows the base to mispair with guanine via the enol tautomer
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Tautomeric forms of the four common bases in DNA.
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Intercalating agents, such as proflavin, acridine, and ethidium, cause the deletion or addition of a base pair or even a few base pairs.