Induce cell division in callus cells in the presence of an auxin

Promote bud or root formation from callus cultures when in the appropriate molar ratios to auxin

Delay senescence of leaves

Promote expansion of dicot cotyledons

TLS Online TPP Program

#Id: 8598

#Unit 2. Cellular Organization

Labile factors called cyclins drive the progression of cells through different stages of the cell cycle by binding to CDKs.

TLS Online TPP Program

#Id: 8599

#Unit 2. Cellular Organization

Cells commit to a new cell division at a specific point in G1 known as START or the restriction point.

TLS Online TPP Program

#Id: 8600

#Unit 2. Cellular Organization

R-factor 

In mammalian cells - cyclin D 

In yeast - Cln3

TLS Online TPP Program

#Id: 8601

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8602

#Unit 2. Cellular Organization

cyclin-CDK complexes preferentially phosphorylate

serine and threonine residues when they are found within the consensus sequence:

[S/T]PX[R/K]K 

TLS Online TPP Program

#Id: 8603

#Unit 2. Cellular Organization

G1 Cyclin–CDKs

In human - cyclin D-CDK 4 

cyclin D-CDK 6

In budding yeast - CIn 3-Cdc 28