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G1 Cyclin–CDKs
In human - cyclin D-CDK 4 
cyclin D-CDK 6
In budding yeast - CIn 3-Cdc 28 

#Unit 2. Cellular Organization #CELL CYCLE #Part B Pointers
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#Unit 5. Developmental Biology

Each pluripotent neoblast generates a colony of neoblast cells in the flatworm.

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#Unit 2. Cellular Organization

Genetic redundancy means that two or more genes are performing the same function and that inactivation of one of these genes has little or no effect on the biological phenotype

Redundancy seems to be widespread in genomes of higher organisms

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#Unit 2. Cellular Organization

M6P residues are generated in the cis-Golgi by two Golgi-resident enzymes. 
  1. N-acetylglucosamine (GlcNAc) phosphotransferase
  2. Phosphodiesterase

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#Unit 2. Cellular Organization

If Amphitelic attachment occur  Microtubules pull kinetochores; cohesins resist this pulling force. The resulting tension leads to the outer kinetochore component Ndc80 being pulled away from the protein kinase Aurora B

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#Unit 7. System Physiology – Animal

Glucocorticoids promote osteoclast activity and bone resorption by :
1. Increasing RANKL production 
2. Decreasing formation of OPG

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