Class II MHC transcriptional activator called CIITA and another transcription factor called RFX, have both been shown to activate the promoter of class II MHC genes.

Defects in these transcription factors cause one form of bare lymphocyte syndrome.

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

p53

extremely unstable protein and generally does not accumulate to high enough levels to stimulate transcription under normal conditions

TLS Online TPP Program

#Id: 1426

#Unit 4. Cell Communication and Cell Signaling

I-domains also recognize CAMs on other cells,  ICAMs, VCAMs and participate in cell-cell adhesion.

TLS Online TPP Program

#Id: 3990

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 9211

#Unit 11. Evolution and Behavior

THE MAGNITUDE OF GENETIC DRIFT

n  = population size

pq=allelic frequency

sp2=variance in allelic frequency among the populations

TLS Online TPP Program

#Id: 6280

#Unit 3. Fundamental Processes

Core enzyme binds indiscriminately to any DNA. Sigma factor reduces the affinity for sequence-independent binding and confers specificity for promoters.