Cockayne syndrome can be caused by mutations in either of two genes (CSA and CSB), both of whose products appear to be part of or bound to TFIIH, and can also be caused by specific mutations in XPB or XPD.

TLS Online TPP Program

#Id: 1737

#Unit 4. Cell Communication and Cell Signaling

Class I MHC, glycoproteins expressed on the surface of nearly all nucleated cells; the major function of the class I is presentation of endogenous peptide antigens to CD8+ T cells.

TLS Online TPP Program

#Id: 1738

#Unit 4. Cell Communication and Cell Signaling

Class II MHC glycoproteins expressed predominantly on pAPCs, where they primarily present exogenous antigenic peptides to CD4+ T cells.

TLS Online TPP Program

#Id: 1739

#Unit 4. Cell Communication and Cell Signaling

Class III MHC genes encode several different proteins, some with immune functions, include the complement components C4, C2, and factor B, TNF-α and Lymphotoxin-α [TNF- α].

TLS Online TPP Program

#Id: 1740

#Unit 4. Cell Communication and Cell Signaling

Daudi tumor cells, which are unable to synthesize β 2-microglobulin.

TLS Online TPP Program

#Id: 1741

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 1742

#Unit 4. Cell Communication and Cell Signaling

MHC-Peptide Interaction