Engulfment involves the assembly of a halo of actin in the engulfing cell around the dying cell, triggered by activation of Rac.

TLS Online TPP Program

#Id: 10391

#Unit 4. Cell Communication and Cell Signaling

Cancer cells 

acquire a drive to proliferate 

does not require an external inducing signal

fail to sense signals that restrict cell division

survive when they should die

TLS Online TPP Program

#Id: 4321

#Unit 11. Evolution and Behavior

Italian physician Francesco Redi (1626–1697),

His hypothesis was supported when maggots developed in the uncovered jars, but no

maggots appeared in either the gauze-covered or the tightly sealed jars. He concluded that

maggots could only form when flies were allowed to lay eggs in the meat, and that the

maggots were the offspring of flies, not the product of spontaneous generation.

TLS Online TPP Program

#Id: 10025

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 2415

#Unit 3. Fundamental Processes

Rho-independent terminators, also called intrinsic terminators because they need no other factors to work, consist of two sequence elements: a short-inverted repeat (of 20 nucleotides) followed by a stretch of about eight A:T base pairs.

TLS Online TPP Program

#Id: 5918

#Unit 3. Fundamental Processes

The holoenzyme assembles on replication fork DNA in three stages:

1. First the clamp loader uses hydrolysis of ATP to bind b subunits to a template primer complex.

2. Binding to DNA changes the conformation of the site on b that binds to the clamp loader, and as a result it now has a high affinity for the core polymerase

3. A t dimer binds to the core polymerase, and provides a dimerization function that binds a second core polymerase