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TLS Online TPP Program

#Id: 10518

Caspases function as homodimers with one domain of each stabilizing the active site of the other; they mediate apoptosis by proteolytic cleavage of selected substrates

#Unit 4. Cell Communication and Cell Signaling #Apoptosis #Part B Pointers
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TLS Online TPP Program

#Id: 7917

#Unit 2. Cellular Organization

Brown Adipose Tissue
is brown because of the presence of large numbers of mitochondria (high concentrations of cytochromes), with heme groups that are strong absorbers of visible 
TLS Online TPP Program

#Id: 7918

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 7919

#Unit 2. Cellular Organization

The mitochondria of brown adipocytes have a unique protein in their inner membrane, Thermogenin (uncoupling protein 1 ), provides a path for protons to return to the matrix without passing through the FoF1 complex.
TLS Online TPP Program

#Id: 7920

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 7921

#Unit 2. Cellular Organization

Thermogenin activity is responsible for one of the principal functions of BAT: Thermogenesi
TLS Online TPP Program

#Id: 7922

#Unit 2. Cellular Organization

Cardiolipin

an unusual “double” phospholipid containing four fatty acid chains

found primarily in the inner mitochondrial membrane

acts to improve the efficiency of oxidative phosphorylation, by restricting proton flow across the membrane